STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sthASoluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (468 aa)    
Predicted Functional Partners:
mazG
Nucleoside triphosphate pyrophosphohydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
 
  
 0.919
pntA
Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.918
pntB
Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.916
cobB
Deacetylase of acetyl-CoA synthetase, NAD-dependent; Protein involved in DNA binding, cobalamin biosynthetic process and regulation of transcription, DNA-dependent; Belongs to the sirtuin family. Class III subfamily.
  
 0.914
nadR
NadR transcriptional repressor / ribosylnicotinamide kinase / NMN adenylyltransferase; NadR is a bifunctional protein that is also involved in the transport of NAD; NadR belongs to the Cro/cI family of transcriptional regulators; Protein involved in transcription repressor activity, DNA binding, transcription regulator activity, catalytic activity, sequence-specific DNA binding, NAD biosynthetic process, transcription, transport, pyridine nucleotide biosynthetic process, regulation of transcription and biosynthetic process.
  
  
  0.912
yfjB
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.911
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.903
nudC
NADH pyrophosphatase; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity and (DEPRECATED) biological process unknown; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.902
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.901
sucA
2-oxoglutarate decarboxylase, thiamin-requiring; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, tricarboxylic acid cycle and metabolic process.
 
 0.893
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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