STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rffGdTDP-glucose 4,6-dehydratase; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, catalytic activity, coenzyme binding, dTDP-glucose 4,6-dehydratase activity, O antigen biosynthetic process, enterobacterial common antigen biosynthetic process, NAD biosynthetic process, cellular metabolic process and nucleotide-sugar metabolic process; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa)    
Predicted Functional Partners:
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
rffH
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.999
rfbD
dTDP-4-dehydrorhamnose reductase; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, dTDP-4-dehydrorhamnose reductase activity, magnesium ion binding, inorganic diphosphatase activity, O antigen biosynthetic process, nucleotide-sugar biosynthetic process, extracellular polysaccharide biosynthetic process and phosphate metabolic process.
 
 
 0.998
rffA
dTDP-4-keto-6-deoxy-D-glucose aminotransferase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.
 
 
 0.966
ugd
UDP-glucose dehydrogenase; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, colanic acid biosynthetic process, response to desiccation, nucleotide-sugar biosynthetic process and (OBSOLETE) electron transport.
  
  
 0.888
wzxE
Lipid III translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
  
  
 0.738
ADM97621.1
Membrane protein involved in the export of O-antigen, teichoic acid lipoteichoic acids; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, O antigen biosynthetic process and polysaccharide biosynthetic process.
  
  
 0.738
rffE
UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
  
  
 0.680
vioA
Nucleotide sugar transaminase; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, catalytic activity, pyridoxal phosphate binding and O antigen biosynthetic process; Belongs to the DegT/DnrJ/EryC1 family.
  
 0.678
rfbN
O antigen biosynthesis rhamnosyltransferase rfbN; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown.
  
  
 0.655
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.