STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppAProtease IV (signal peptide peptidase); Protein involved in (OBSOLETE) signal peptidase activity, peptidase activity, signal peptide processing and proteolysis. (616 aa)    
Predicted Functional Partners:
ansA
Cytoplasmic L-asparaginase I; Protein involved in asparaginase activity, amino acid catabolic process and amino acid metabolic process.
       0.522
trpC
Protein involved in catalytic activity, indole-3-glycerol-phosphate synthase activity, phosphoribosylanthranilate isomerase activity, tryptophan biosynthetic process, metabolic process and tryptophan metabolic process; Belongs to the TrpC family.
     
 0.472
ydjA
Predicted oxidoreductase; Protein involved in (DEPRECATED) molecular function unknown, oxidoreductase activity, (DEPRECATED) biological process unknown and (OBSOLETE) electron transport.
       0.465
pncA
Nicotinamidase/pyrazinamidase; Protein involved in catalytic activity and metabolic process.
       0.427
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
     
 0.401
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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