STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF4Interferon regulatory factor 4. (446 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor associated factor 6.
   
 0.680
LOC106900055
Serine/threonine-protein kinase Sgk3-like.
    
 0.675
LOC106886558
Serine/threonine-protein kinase Sgk3.
    
 0.675
IRF1
Interferon regulatory factor 1.
   
0.647
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.621
SIRT5
Sirtuin 5.
    
 0.585
SIRT1
Sirtuin 1.
    
 0.585
EP300
E1A binding protein p300.
    
 0.580
BCL6
BCL6 transcription repressor.
    
 0.575
SPI1
Spi-1 proto-oncogene.
   
 
 0.572
Your Current Organism:
Calidris pugnax
NCBI taxonomy Id: 198806
Other names: C. pugnax, Machetes pugnax, Pavoncella pugnax, Philomachus pugnax, ruff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.