STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17ADAM metallopeptidase domain 17. (829 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.960
NOTCH1
Notch receptor 1.
    
 0.888
ADAM10
ADAM metallopeptidase domain 10.
     
0.883
NOTCH2
Notch receptor 2.
    
 0.864
FAT3
FAT atypical cadherin 3.
     
 0.809
HBEGF
Heparin binding EGF like growth factor.
     
 0.806
TIMP2
TIMP metallopeptidase inhibitor 2.
    
 0.782
ENSCPUP00000022176
annotation not available
    
 0.751
ENSCPUP00000022179
annotation not available
    
 0.751
LOC106898612
Intestinal mucin-like protein.
    
 0.739
Your Current Organism:
Calidris pugnax
NCBI taxonomy Id: 198806
Other names: C. pugnax, Machetes pugnax, Pavoncella pugnax, Philomachus pugnax, ruff
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.