STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPBP1DNA topoisomerase II binding protein 1. (1495 aa)    
Predicted Functional Partners:
CDC45
Cell division cycle 45.
   
 0.999
BRCA1
BRCA1 DNA repair associated.
   
 0.998
MCM5
Minichromosome maintenance complex component 5.
   
 0.996
MCM3
Minichromosome maintenance complex component 3.
   
 0.994
LOC106893757
BRCA1-associated RING domain protein 1-like.
   
 0.994
ENSCPUP00000025694
annotation not available
   
 0.994
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.993
ATR
ATR serine/threonine kinase.
    
 0.990
WRN
WRN RecQ like helicase.
   
 0.990
GINS1
GINS complex subunit 1.
   
 0.979
Your Current Organism:
Calidris pugnax
NCBI taxonomy Id: 198806
Other names: C. pugnax, Machetes pugnax, Pavoncella pugnax, Philomachus pugnax, ruff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.