STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK9Proprotein convertase subtilisin/kexin type 9. (642 aa)    
Predicted Functional Partners:
LRP8
LDL receptor related protein 8.
    
 0.940
VLDLR
Very low density lipoprotein receptor.
    
 0.940
PI4KA
Phosphatidylinositol 4-kinase alpha.
    
 0.937
ANXA2
Annexin A2.
    
 0.931
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
   
 0.899
PI4KB
Phosphatidylinositol 4-kinase beta.
    
 0.882
INPPL1
Inositol polyphosphate phosphatase like 1.
    
 0.874
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
    
 0.863
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.850
TNS1
Tensin 1.
     
 0.827
Your Current Organism:
Calidris pugnax
NCBI taxonomy Id: 198806
Other names: C. pugnax, Machetes pugnax, Pavoncella pugnax, Philomachus pugnax, ruff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.