STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE2DNA polymerase epsilon 2, accessory subunit. (527 aa)    
Predicted Functional Partners:
POLE
DNA polymerase epsilon, catalytic subunit.
   
 0.999
POLE3
DNA polymerase epsilon 3, accessory subunit.
    
 0.998
MCM2
Minichromosome maintenance complex component 2.
   
 0.998
CDC45
Cell division cycle 45.
   
 0.997
POLA1
DNA polymerase alpha 1, catalytic subunit.
   
 0.997
MCM4
Minichromosome maintenance complex component 4.
   
 0.997
MCM3
Minichromosome maintenance complex component 3.
   
 0.995
MCM6
Minichromosome maintenance complex component 6.
   
 0.995
MCM5
Minichromosome maintenance complex component 5.
   
 0.995
ENSCPUP00000000143
annotation not available
   
 
 0.994
Your Current Organism:
Calidris pugnax
NCBI taxonomy Id: 198806
Other names: C. pugnax, Machetes pugnax, Pavoncella pugnax, Philomachus pugnax, ruff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.