STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFN98267.1DNA-binding transcriptional regulator, Lrp family. (151 aa)    
Predicted Functional Partners:
SFN90742.1
DNA-binding transcriptional regulator, Lrp family.
  
     0.773
SFO88929.1
uroporphyrinogen-III C-methyltransferase.
  
 
 0.669
SFN98321.1
Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
       0.637
SFN99352.1
Transcriptional regulator, AsnC family.
  
     0.625
SFO09615.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.580
SFN98225.1
Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.559
SFO47565.1
Anthranilate synthase, component I.
   
 
  0.526
SFN81948.1
DNA-binding transcriptional regulator, HxlR family.
   
    0.485
SFO21860.1
DNA-binding transcriptional regulator, HxlR family.
   
    0.485
SFP75843.1
DNA-binding transcriptional regulator, HxlR family.
   
    0.485
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.