STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO35973.1Catechol 2,3-dioxygenase. (222 aa)    
Predicted Functional Partners:
SFO36013.1
Hypothetical protein.
 
     0.950
maiA
Maleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
 
     0.928
SFO36076.1
anthraniloyl-CoA monooxygenase.
 
  
 0.890
SFO36055.1
N-methylhydantoinase B.
 
     0.841
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.790
SFO35994.1
Hypothetical protein.
       0.789
SFQ22636.1
Hypothetical protein.
 
     0.788
SFO35928.1
DNA-binding transcriptional regulator, AcrR family.
 
     0.783
SFP05524.1
Hypothetical protein.
 
     0.768
SFO36099.1
Non-ribosomal peptide synthetase component E (peptide arylation enzyme).
 
     0.700
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.