STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO54424.12-ketocyclohexanecarboxyl-CoA hydrolase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)    
Predicted Functional Partners:
SFO54401.1
crotonobetaine/carnitine-CoA ligase.
 
  
  0.926
SFO58652.1
Methyltransferase domain-containing protein.
    
 0.831
SFO54378.1
Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
     0.831
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.778
SFQ37819.1
8-amino-7-oxononanoate synthase.
    
 0.766
SFN32825.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
    
 0.701
SFN60854.1
Amino acid adenylation domain-containing protein.
    
 0.701
SFN60883.1
Non-ribosomal peptide synthase domain TIGR01720.
    
 0.701
SFP69552.1
Amino acid adenylation domain-containing protein.
    
 0.701
menB
1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
  
  
 
0.697
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
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