STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa)    
Predicted Functional Partners:
SFO65611.1
Dethiobiotin synthetase.
 
 
 0.998
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
 0.996
SFP31697.1
Putrescine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.933
SFO65562.1
8-amino-7-oxononanoate synthase.
 
 0.931
SFN80468.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
 
 0.890
SFN64045.1
CAI-1 autoinducer synthase.
 
 
 0.881
SFQ37769.1
8-amino-7-oxononanoate synthase.
 
 0.864
SFQ12303.1
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.855
SFN98225.1
Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 
 0.691
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
 
 0.669
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
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