node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFN79389.1 | SFO43419.1 | SAMN04489713_10361 | SAMN04489713_10620 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | IMP dehydrogenase. | 0.617 |
SFN79389.1 | SFO93534.1 | SAMN04489713_10361 | SAMN04489713_110290 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative hydrolase of the HAD superfamily. | 0.798 |
SFN79389.1 | SFP42424.1 | SAMN04489713_10361 | SAMN04489713_11431 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.871 |
SFN79389.1 | SFP77238.1 | SAMN04489713_10361 | SAMN04489713_117123 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | IMP dehydrogenase. | 0.606 |
SFN79389.1 | apt | SAMN04489713_10361 | SAMN04489713_12348 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.923 |
SFN79389.1 | guaA | SAMN04489713_10361 | SAMN04489713_117114 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.626 |
SFN79389.1 | guaB | SAMN04489713_10361 | SAMN04489713_117124 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.793 |
SFN79389.1 | nadD | SAMN04489713_10361 | SAMN04489713_110330 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.666 |
SFN79389.1 | upp | SAMN04489713_10361 | SAMN04489713_121131 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.905 |
SFO43419.1 | SFN79389.1 | SAMN04489713_10620 | SAMN04489713_10361 | IMP dehydrogenase. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.617 |
SFO43419.1 | SFO93534.1 | SAMN04489713_10620 | SAMN04489713_110290 | IMP dehydrogenase. | Putative hydrolase of the HAD superfamily. | 0.796 |
SFO43419.1 | SFP77238.1 | SAMN04489713_10620 | SAMN04489713_117123 | IMP dehydrogenase. | IMP dehydrogenase. | 0.879 |
SFO43419.1 | apt | SAMN04489713_10620 | SAMN04489713_12348 | IMP dehydrogenase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.883 |
SFO43419.1 | guaA | SAMN04489713_10620 | SAMN04489713_117114 | IMP dehydrogenase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.999 |
SFO43419.1 | guaB | SAMN04489713_10620 | SAMN04489713_117124 | IMP dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.908 |
SFO93534.1 | SFN79389.1 | SAMN04489713_110290 | SAMN04489713_10361 | Putative hydrolase of the HAD superfamily. | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.798 |
SFO93534.1 | SFO43419.1 | SAMN04489713_110290 | SAMN04489713_10620 | Putative hydrolase of the HAD superfamily. | IMP dehydrogenase. | 0.796 |
SFO93534.1 | SFO93572.1 | SAMN04489713_110290 | SAMN04489713_110291 | Putative hydrolase of the HAD superfamily. | Pimeloyl-ACP methyl ester carboxylesterase. | 0.814 |
SFO93534.1 | SFP42424.1 | SAMN04489713_110290 | SAMN04489713_11431 | Putative hydrolase of the HAD superfamily. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.796 |
SFO93534.1 | SFP77238.1 | SAMN04489713_110290 | SAMN04489713_117123 | Putative hydrolase of the HAD superfamily. | IMP dehydrogenase. | 0.801 |