STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP31606.1hydroxymethylglutaryl-CoA lyase. (317 aa)    
Predicted Functional Partners:
SFQ42990.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.978
SFP87187.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 0.895
SFP31537.1
enoyl-CoA hydratase.
 
 
  0.877
SFP31588.1
Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
  0.877
SFO48134.1
Biotin-requiring enzyme.
 
 0.853
SFP31513.1
fatty-acyl-CoA synthase.
 
  0.834
SFO67242.1
Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase.
 
 0.825
SFP31558.1
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB; Belongs to the CoA-transferase III family.
  
  0.812
SFO49258.1
2-oxoisovalerate dehydrogenase E1 component.
 
 
 0.805
SFN05510.1
3-isopropylmalate dehydrogenase.
  
 0.798
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.