STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP57051.1Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)    
Predicted Functional Partners:
SFP33704.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.813
SFN13497.1
Malate synthase; Belongs to the malate synthase family.
  
 
 0.812
SFN05426.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
0.797
SFO64081.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
   
 
 0.796
SFO46475.1
Isocitrate lyase.
     
 0.788
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.784
SFN24441.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.770
SFN12401.1
Competence/damage-inducible protein cinA; Belongs to the CinA family.
  
    0.767
SFN16983.1
Glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.765
SFN94224.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.765
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
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