STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP85372.1Sodium:solute symporter family protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (576 aa)    
Predicted Functional Partners:
SFP85406.1
Uncharacterized membrane protein, DUF485 family.
 
  
 0.969
SFP85344.1
Protein of unknown function, DUF485.
 
     0.949
SFP85316.1
DNA-binding response regulator, LytR/AlgR family.
 
     0.871
SFP85287.1
Two-component system, LytT family, sensor kinase.
 
     0.860
SFN19795.1
Two-component system, LytT family, sensor kinase.
 
     0.776
SFN19818.1
DNA-binding response regulator, LytR/AlgR family.
 
     0.764
SFP85436.1
Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    
0.659
SFO86903.1
Acetyl-coenzyme A synthetase.
  
  
 0.546
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.546
SFN85465.1
acetoacetyl-CoA synthetase.
  
  
 0.528
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
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