STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFQ43258.1DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family. (263 aa)    
Predicted Functional Partners:
SFO57080.1
Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.842
SFQ10139.1
Acyl-CoA synthetase (NDP forming).
    
   0.814
SFO45542.1
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.806
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
  0.675
SFO90181.1
Ribose 5-phosphate isomerase B.
  
 
 0.649
SFQ43323.1
Xylulokinase; Belongs to the FGGY kinase family.
 
  
 0.622
SFQ43339.1
Sugar (pentulose or hexulose) kinase.
 
  
 0.597
SFQ43242.1
Glutathione S-transferase.
       0.511
SFN56479.1
5-deoxyglucuronate isomerase.
  
  
 0.507
SFQ43275.1
Monosaccharide ABC transporter substrate-binding protein, CUT2 family.
       0.463
Your Current Organism:
Actinomadura madurae
NCBI taxonomy Id: 1993
Other names: A. madurae, ATCC 19425, CCM 136, CCUG 32944, CECT 3043, CIP 105487, DSM 43067, IAM 14277, IFM 0585, IFO 13909, IFO 14623, IMET 9585, JCM 7436, KCTC 9192, NBRC 14623, NCIMB 13469, NCTC 5654, NRRL B-3843, Nocardia madurae, Streptomyces madurae, Streptothrix madurae, VKM Ac-809
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.