STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaRTranscriptional activator protein nhaR; Na+/H+ antiporter regulatory protein; Escherichia coli K-12 ortholog: b0020; Escherichia coli O157:H7 ortholog: z0019; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
nhaA
Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
  
 0.951
ybjN
Hypothetical protein ybjN; Escherichia coli K-12 ortholog: b0853; Escherichia coli O157:H7 ortholog: z1080.
  
     0.443
yebT
Hypothetical protein yebT; Escherichia coli K-12 ortholog: b1834; Escherichia coli O157:H7 ortholog: z2881.
  
     0.411
ycdS
Hypothetical protein ycdS precursor; Escherichia coli K-12 ortholog: b1024; Escherichia coli O157:H7 ortholog: z1526.
      
 0.404
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
     
 0.403
yadL
Hypothetical protein yadL precursor; Escherichia coli K-12 ortholog: b0137; Escherichia coli O157:H7 ortholog: z0148.
      
 0.402
codA
Cytosine deaminase; Escherichia coli K-12 ortholog: b0337; Escherichia coli O157:H7 ortholog: z0433.
      
 0.402
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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