STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citFCitrate lyase alpha chain; Escherichia coli K-12 ortholog: b0615; Escherichia coli O157:H7 ortholog: z0759. (510 aa)    
Predicted Functional Partners:
citE
Citrate lyase beta chain; Represents a citryl-ACP lyase; Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
 
 
 0.999
ybdU
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein; Belongs to the CitX family.
 
  
 0.990
citC
[Citrate [pro-3S]-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
  
 0.980
citG
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family.
 
  
 0.948
c0761
Putative dihydrodipicolinate synthase; Residues 11 to 294 of 295 are 43.50 pct identical to residues 8 to 292 of 297 from GenPept.129 : >gb|AAL45759.1| (AE008931) dihydrodipicolinate synthase [Agrobacterium tumefaciens str. C58 (U. Washington)]; Belongs to the DapA family.
   
    0.650
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
   
    0.650
nanA2
N-acetylneuraminate lyase subunit; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
   
    0.650
nanA
N-acetylneuraminate lyase subunit; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
   
    0.650
c0705
Hypothetical protein.
       0.572
ydbK
Probable pyruvate-flavodoxin oxidoreductase; Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332.
      
 0.527
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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