STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycbJHypothetical protein ycbJ; Escherichia coli K-12 ortholog: b0919; Escherichia coli O157:H7 ortholog: z1265. (297 aa)    
Predicted Functional Partners:
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
      0.773
ygaC
Hypothetical protein ygaC; Escherichia coli K-12 ortholog: b2671; Escherichia coli O157:H7 ortholog: z3971.
  
     0.770
ampE
AmpE protein; Escherichia coli K-12 ortholog: b0111; Escherichia coli O157:H7 ortholog: z0121.
  
     0.761
yiaF
Hypothetical protein yiaF; Escherichia coli K-12 ortholog: b3554; Escherichia coli O157:H7 ortholog: z4979.
  
     0.757
yjbO
Hypothetical protein yjbO; Escherichia coli K-12 ortholog: b4050; Escherichia coli O157:H7 ortholog: z5648.
  
     0.756
rcsF
Protein rcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.751
yobD
Hypothetical protein yobD; Escherichia coli K-12 ortholog: b1820; Escherichia coli O157:H7 ortholog: z2863.
  
     0.746
yniB
Hypothetical protein yniB; Escherichia coli K-12 ortholog: b1726; Escherichia coli O157:H7 ortholog: z2755.
  
     0.725
yceB
Putative lipoprotein yceB precursor; Escherichia coli K-12 ortholog: b1063; Escherichia coli O157:H7 ortholog: z1700.
  
     0.723
yicH
Hypothetical protein yicH; Escherichia coli K-12 ortholog: b3655; Escherichia coli O157:H7 ortholog: z5083.
  
     0.722
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.