STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyaEHydrogenase-1 operon protein hyaE; Escherichia coli K-12 ortholog: b0976; Escherichia coli O157:H7 ortholog: z1393. (132 aa)    
Predicted Functional Partners:
hyaF
Hydrogenase-1 operon protein hyaF; Escherichia coli K-12 ortholog: b0977; Escherichia coli O157:H7 ortholog: z1394.
 
  
 0.999
hyaD
Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.
 
  
 0.998
hyaC
Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit; Escherichia coli K-12 ortholog: b0974; Escherichia coli O157:H7 ortholog: z1391.
 
  
 0.997
hyaA
Hydrogenase-1 small chain precursor; This is one of three E.coli hydrogenases synthesized in response to different physiological conditions. HYD1 is believed to have a role in hydrogen cycling during fermentative growth.
 
 
 0.993
hyaB
Hydrogenase-1 large chain; Escherichia coli K-12 ortholog: b0973; Escherichia coli O157:H7 ortholog: z1390; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.992
hybE
Hydrogenase-2 operon protein hybE; Escherichia coli K-12 ortholog: b2992; Escherichia coli O157:H7 ortholog: z4346; Belongs to the HupJ family.
 
  
 0.858
ycgK
Protein ycgK precursor; Escherichia coli K-12 ortholog: b1178; Escherichia coli O157:H7 ortholog: z1940.
  
     0.773
c3630
Hypothetical protein yjhS precursor; Escherichia coli K-12 ortholog: b4309.
  
     0.764
torD
Chaperone protein torD; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.
  
     0.760
appC
Cytochrome BD-II oxidase subunit I; Escherichia coli K-12 ortholog: b0978; Escherichia coli O157:H7 ortholog: z1395.
  
  
 0.759
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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