STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsGPTS system, glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. (477 aa)    
Predicted Functional Partners:
crr
PTS system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
 0.999
mlc
Mlc protein; Making large colonies protein; Escherichia coli K-12 ortholog: b1594; Escherichia coli O157:H7 ortholog: z2587.
  
 
 0.994
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.991
glk
Glucokinase; Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
    
 0.972
c4758
PTS system, glucose-specific IIBC component; EIIBC-Glc; Escherichia coli K-12 ortholog: b1101; Escherichia coli O157:H7 ortholog: z1740.
 
0.966
pgi
Glucose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b4025; Escherichia coli O157:H7 ortholog: z5623.
    
 0.957
c3408
Maltose and glucose-permease IIABC component; Escherichia coli K-12 ortholog: b1621; Escherichia coli O157:H7 ortholog: z2626.
 
 
0.929
malX
Maltose and glucose-permease IIABC component; Escherichia coli K-12 ortholog: b1621; Escherichia coli O157:H7 ortholog: z2626.
 
 
0.927
pgm
Phosphoglucomutase; Escherichia coli K-12 ortholog: b0688; Escherichia coli O157:H7 ortholog: z0837.
    
 0.918
c4283
Putative phosphocarrier protein; Escherichia coli O157:H7 ortholog: z4879.
  
 
 0.917
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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