STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ynfDHypothetical protein ynfD precursor; Escherichia coli K-12 ortholog: b1586; Escherichia coli O157:H7 ortholog: z2573. (115 aa)    
Predicted Functional Partners:
yidQ
Hypothetical protein yidQ precursor; Escherichia coli K-12 ortholog: b3688; Escherichia coli O157:H7 ortholog: z5184.
  
     0.734
yggN
Hypothetical protein yggN; Escherichia coli K-12 ortholog: b2958; Escherichia coli O157:H7 ortholog: z4303.
  
     0.706
ynfB
Hypothetical protein ynfB precursor; Escherichia coli K-12 ortholog: b1583; Escherichia coli O157:H7 ortholog: z2570; Belongs to the UPF0482 family.
 
     0.698
yacC
Hypothetical protein yacC precursor; Escherichia coli K-12 ortholog: b0122; Escherichia coli O157:H7 ortholog: z0132.
  
     0.691
yacA
Secretion monitor precursor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.
  
     0.685
yraM
Hypothetical protein yraM; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
  
     0.667
yqjE
Hypothetical protein yqjE; Escherichia coli K-12 ortholog: b3099; Escherichia coli O157:H7 ortholog: z4453.
  
     0.656
yceP
Hypothetical protein yceP; Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway (By similarity).
  
     0.643
yeiU
Hypothetical protein yeiU; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
  
     0.632
ypfN
Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z3731.
  
     0.630
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.