STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhLHypothetical protein ydhL precursor; Escherichia coli K-12 ortholog: b1648; Escherichia coli O157:H7 ortholog: z2665. (125 aa)    
Predicted Functional Partners:
yfaE
Hypothetical ferredoxin-like protein yfaE; Escherichia coli K-12 ortholog: b2236; Escherichia coli O157:H7 ortholog: z3492.
  
     0.666
nrdB
Ribonucleoside-diphosphate reductase 1 beta chain; Escherichia coli K-12 ortholog: b2235; Escherichia coli O157:H7 ortholog: z3491.
  
     0.658
nrdA
Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
     0.641
ydhF
Hypothetical oxidoreductase ydhF; Escherichia coli K-12 ortholog: b1647; Escherichia coli O157:H7 ortholog: z2664.
       0.629
yihI
Hypothetical protein yihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.625
yqjC
Protein yqjC precursor; Escherichia coli K-12 ortholog: b3097; Escherichia coli O157:H7 ortholog: z4451.
  
     0.593
yfbV
Hypothetical protein yfbV; Escherichia coli K-12 ortholog: b2295; Escherichia coli O157:H7 ortholog: z3556.
  
     0.580
ydhM
Hypothetical transcriptional regulator ydhM; Involved in response to both electrophiles and reactive chlorine species (RCS). Represses the transcription of the nemRA-gloA operon by binding to the NemR box.
     
 0.578
sodC
Superoxide dismutase [Cu-Zn] precursor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
       0.553
ybcI
Hypothetical protein ybcI; Escherichia coli K-12 ortholog: b0527; Escherichia coli O157:H7 ortholog: z0682.
      
 0.548
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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