STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydiMHypothetical transport protein ydiM; Escherichia coli K-12 ortholog: b1690; Escherichia coli O157:H7 ortholog: z2718. (404 aa)    
Predicted Functional Partners:
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
     0.836
ydiB
Hypothetical shikimate 5-dehydrogenase-like protein ydiB; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
 
   
 0.832
ydiL
Hypothetical protein ydiL; Escherichia coli K-12 ortholog: b1689; Escherichia coli O157:H7 ortholog: z2717.
     
 0.661
yehR
Hypothetical lipoprotein yehR precursor; Escherichia coli K-12 ortholog: b2123; Escherichia coli O157:H7 ortholog: z3300.
  
     0.604
yehI
Hypothetical protein yehI; Escherichia coli K-12 ortholog: b2118; Escherichia coli O157:H7 ortholog: z3287.
      
 0.574
gutM
Glucitol operon activator protein; Escherichia coli K-12 ortholog: b2706; Escherichia coli O157:H7 ortholog: z4013.
  
     0.548
ydiN
Hypothetical transport protein ydiN; Escherichia coli K-12 ortholog: b1691; Escherichia coli O157:H7 ortholog: z2719.
 
   
0.540
c4986
D-glucitol-6-phosphate dehydrogenase; Escherichia coli O157:H7 ortholog: z5618; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.509
srlE
PTS system, glucitol/sorbitol-specific IIBC component; EIIBC-GUT; Escherichia coli K-12 ortholog: b2703; Escherichia coli O157:H7 ortholog: z4009.
  
    0.477
srlA
PTS system, glucitol/sorbitol-specific IIC2 component; EIIC2-GUT; Escherichia coli K-12 ortholog: b2702; Escherichia coli O157:H7 ortholog: z4005.
  
    0.472
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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