STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pfkB6-phosphofructokinase isozyme 2; Escherichia coli K-12 ortholog: b1723; Escherichia coli O157:H7 ortholog: z2752; Belongs to the carbohydrate kinase PfkB family. (310 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose-specific IIBC component; EIIBC-Fru; Escherichia coli K-12 ortholog: b2167; Escherichia coli O157:H7 ortholog: z3425.
 
  
 0.991
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.981
fbaB
Fructose-bisphosphate aldolase class I; Escherichia coli K-12 ortholog: b2097; Escherichia coli O157:H7 ortholog: z3260.
 
 
 0.972
fbp
Fructose-1,6-bisphosphatase; Escherichia coli K-12 ortholog: b4232; Escherichia coli O157:H7 ortholog: z5842.
     
 0.968
fryA
Putative phosphoenolpyruvate-protein phosphotransferase ypdD; Multifunctional protein that includes general (non sugar- specific) and sugar-specific components of the phosphoenolpyruvate- dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport.
  
  
 0.945
ptsA
Phosphoenolpyruvate-protein phosphotransferase ptsA; Escherichia coli K-12 ortholog: b3947; Escherichia coli O157:H7 ortholog: z5502.
  
  
 0.945
pgi
Glucose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b4025; Escherichia coli O157:H7 ortholog: z5623.
    
 0.941
srlD
Sorbitol-6-phosphate 2-dehydrogenase; Escherichia coli K-12 ortholog: b2705; Escherichia coli O157:H7 ortholog: z4012; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.933
c4986
D-glucitol-6-phosphate dehydrogenase; Escherichia coli O157:H7 ortholog: z5618; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.933
fruK
1-phosphofructokinase; Escherichia coli K-12 ortholog: b2168; Escherichia coli O157:H7 ortholog: z3426; Belongs to the carbohydrate kinase PfkB family.
  
  
 
0.926
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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