STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
astAArginine N-succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. (315 aa)    
Predicted Functional Partners:
astB
Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
 
 
 0.998
cstC
Succinylornithine transaminase; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
 
  
 0.997
astD
Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
 
  
 0.995
ydjS
Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
 
  
 0.965
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
  
  
  0.911
c4501
Putative conserved protein; Residues 7 to 750 of 789 are 38.82 pct identical to residues 4 to 744 of 756 from MG1655 : b4117.
   
 
 0.909
adiA
Biodegradative arginine decarboxylase; Escherichia coli K-12 ortholog: b4117; Escherichia coli O157:H7 ortholog: z5719.
   
 
 0.909
arcA-2
Putative arginine deiminase; Residues 7 to 407 of 407 are 47.79 pct identical to residues 10 to 416 of 418 from SwissProt.40 : >sp|P13981|ARCA_PSEAE Arginine deiminase (ADI) (Arginine dihydrolase) (AD).
     
 0.900
argH
Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518.
     
 0.868
argD
Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways.
 
  
 0.683
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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