STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcZHypothetical protein yfcZ; Escherichia coli K-12 ortholog: b2343; Escherichia coli O157:H7 ortholog: z3606; Belongs to the UPF0381 family. (102 aa)    
Predicted Functional Partners:
yhdT
Hypothetical protein yhdT; Escherichia coli K-12 ortholog: b3257; Escherichia coli O157:H7 ortholog: z4617.
  
     0.772
smp
Protein smp precursor; Escherichia coli K-12 ortholog: b4387.
  
     0.729
ybgE
Protein ybgE; Escherichia coli K-12 ortholog: b0735; Escherichia coli O157:H7 ortholog: z0903.
  
     0.728
wzzE
Lipopolysaccharide biosynthesis protein wzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.
  
     0.722
yafA
Hypothetical protein yafA; Displays esterase activity toward pNP-butyrate.
  
     0.707
ycbW
Hypothetical protein ycbW; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.705
yciS
Hypothetical protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.704
yciN
Protein yciN; Escherichia coli K-12 ortholog: b1273; Escherichia coli O157:H7 ortholog: z2537.
  
     0.703
yihD
Protein yihD; Escherichia coli K-12 ortholog: b3858; Escherichia coli O157:H7 ortholog: z5390; To H.influenzae HI_0845.
  
     0.686
ydfG
Probable oxidoreductase ydfG; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimidine degradatio [...]
      
 0.683
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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