STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrKMultidrug resistance protein K; Escherichia coli K-12 ortholog: b2368; Escherichia coli O157:H7 ortholog: z3630. (387 aa)    
Predicted Functional Partners:
emrY
Multidrug resistance protein Y; Escherichia coli K-12 ortholog: b2367; Escherichia coli O157:H7 ortholog: z3629; Belongs to the major facilitator superfamily.
 
 0.999
tolC
Outer membrane protein tolC precursor; Escherichia coli K-12 ortholog: b3035; Escherichia coli O157:H7 ortholog: z4392.
  
 0.958
emrB
Multidrug resistance protein B; Escherichia coli K-12 ortholog: b2686; Escherichia coli O157:H7 ortholog: z3987; Belongs to the major facilitator superfamily.
 
 
 0.891
ydeO
Hypothetical transcriptional regulator ydeO; Induces the expression of gadE and mdtEF. Could also regulate the expression of other genes involved in acid resistance (By similarity).
  
  
 0.806
yjcP
Hypothetical outer-membrane lipoprotein yjcP precursor; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
 
 
 0.773
yegM
Hypothetical protein yegM precursor; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.757
c1016
Hypothetical protein; Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) putative ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933].
  
 
 0.745
yieO
Hypothetical transport protein yieO; Escherichia coli K-12 ortholog: b3754; Escherichia coli O157:H7 ortholog: z5255; Belongs to the major facilitator superfamily.
 
 
 0.743
yegB
Hypothetical transport protein yegB; Escherichia coli K-12 ortholog: b2077; Escherichia coli O157:H7 ortholog: z3246.
 
 
 0.741
yhiU
Hypothetical lipoprotein yhiU precursor; Part of the tripartite efflux system MdtEF-TolC, which confers resistance to various compounds.
 
  
 0.731
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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