STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srlAPTS system, glucitol/sorbitol-specific IIC2 component; EIIC2-GUT; Escherichia coli K-12 ortholog: b2702; Escherichia coli O157:H7 ortholog: z4005. (187 aa)    
Predicted Functional Partners:
srlB
PTS system, glucitol/sorbitol-specific IIA component; EIIA-gut; Escherichia coli K-12 ortholog: b2704; Escherichia coli O157:H7 ortholog: z4011.
 
 
 0.999
srlD
Sorbitol-6-phosphate 2-dehydrogenase; Escherichia coli K-12 ortholog: b2705; Escherichia coli O157:H7 ortholog: z4012; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
  0.999
srlE
PTS system, glucitol/sorbitol-specific IIBC component; EIIBC-GUT; Escherichia coli K-12 ortholog: b2703; Escherichia coli O157:H7 ortholog: z4009.
 
 
 0.998
gutM
Glucitol operon activator protein; Escherichia coli K-12 ortholog: b2706; Escherichia coli O157:H7 ortholog: z4013.
 
  
 0.986
c4986
D-glucitol-6-phosphate dehydrogenase; Escherichia coli O157:H7 ortholog: z5618; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
  0.982
c4981
Putative oxidoreductase; Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z5613.
 
  
  0.939
c3514
Putative oxidoreductase; Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z4276.
 
  
  0.931
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
    
  0.902
c4283
Putative phosphocarrier protein; Escherichia coli O157:H7 ortholog: z4879.
    
  0.902
gatC
PTS system, galactitol-specific IIC component; EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z3255.
 
  
 0.784
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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