STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlyDResidues 1 to 478 of 478 are 98.95 pct identical to residues 1 to 478 of 478 from SwissProt.40 : >sp|P09986|HLY4_ECOLI Hemolysin secretion protein D, chromosomal. (478 aa)    
Predicted Functional Partners:
hlyB
Hemolysin B; Part of the ABC transporter complex HlyBD involved in hemolysin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
 
 0.998
hlyA
Hemolysin A; Residues 1 to 1024 of 1024 are 98.63 pct identical to residues 1 to 1023 of 1023 from SwissProt.40 : >sp|P09983|HLY1_ECOLI HEMOLYSIN, CHROMOSOMAL.
 
  
 0.953
hlyC
Hemolysin C; Residues 55 to 224 of 224 are 97.64 pct identical to residues 1 to 170 of 170 from SwissProt.40 : >sp|P09984|HLC1_ECOLI HEMOLYSIN-ACTIVATING LYSINE-ACYLTRANSFERASE HLYC (TOXIN-ACTIVATING PROTEIN C, J96) (HEMOLYSIN C).
 
   
 0.857
c0361
Putative cytoplasmic membrane export protein; Escherichia coli O157:H7 ortholog: z0634.
  
 0.767
c1016
Hypothetical protein; Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) putative ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933].
  
 
 0.745
c0360
Hypothetical protein; Residues 93 to 374 of 415 are 22.55 pct identical to residues 108 to 400 of 445 from GenPept.129 : >gb|AAF94774.1| (AE004240) agglutination protein [Vibrio cholerae].
 
 
 0.627
tolC
Outer membrane protein tolC precursor; Escherichia coli K-12 ortholog: b3035; Escherichia coli O157:H7 ortholog: z4392.
  
 
 0.590
mchF
Probable microcin H47 secretion ATP-binding protein; ABC transporter; Residues 7 to 704 of 704 are 98.71 pct identical to residues 1 to 698 of 698 from SwissProt.40 : >sp|Q9EXN5|MCHF_ECOLI Probable microcin H47 secretion ATP-binding protein mchF.
  
 0.532
c1765
Partial Putative outer membrane channel protein; Escherichia coli O157:H7 ortholog: z2506.
 
 
 0.521
cusC
Probable outer membrane lipoprotein cusC precursor; Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity); Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
 
 0.438
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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