STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
c3803Putative Transposase; Escherichia coli O157:H7 ortholog: z5815. (150 aa)    
Predicted Functional Partners:
ydcM
Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.
 
    0.898
gipA
Peyer's patch-specific virulence factor GipA; Residues 1 to 373 of 376 are 54.52 pct identical to residues 5 to 379 of 402 from SwissProt.40 : >sp|P54992|YSNA_STRPR Hypothetical 45.4 kDa protein in SNAA-SNAB intergenic region (ORF401).
 
    0.757
ygiF
Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.
  
    0.643
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
       0.639
c2425
Hypothetical protein; Residues 2 to 125 of 125 are 93.54 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200.
  
     0.636
c0002
Hypothetical protein; Residues 2 to 125 of 125 are 94.35 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200.
  
     0.604
hldE
ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
     
 0.522
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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