STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygjGProbable ornithine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (496 aa)    
Predicted Functional Partners:
ydcW
Putative betaine aldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
 
 0.984
ldcC
Lysine decarboxylase, constitutive; Escherichia coli K-12 ortholog: b0186; Escherichia coli O157:H7 ortholog: z0198.
   
 
 0.968
speB
Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
 0.938
speC
Ornithine decarboxylase, constitutive; Escherichia coli K-12 ortholog: b2965; Escherichia coli O157:H7 ortholog: z4310.
   
 
 0.920
speG
Spermidine N(1)-acetyltransferase; Escherichia coli K-12 ortholog: b1584; Escherichia coli O157:H7 ortholog: z2571.
   
 
 0.916
speF
Ornithine decarboxylase, inducible; Escherichia coli K-12 ortholog: b0693; Escherichia coli O157:H7 ortholog: z0839.
   
 
 0.911
cadA
Lysine decarboxylase, inducible; Escherichia coli K-12 ortholog: b4131; Escherichia coli O157:H7 ortholog: z5734.
   
 
 0.911
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
 0.909
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.828
argH
Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518.
 
  
 0.822
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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