STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxaCUronate isomerase; Escherichia coli K-12 ortholog: b3092; Escherichia coli O157:H7 ortholog: z4445. (491 aa)    
Predicted Functional Partners:
uxuB
D-mannonate oxidoreductase; Escherichia coli K-12 ortholog: b4323; Escherichia coli O157:H7 ortholog: z5921; Belongs to the mannitol dehydrogenase family.
 
 
 0.995
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.994
uxaA
Altronate hydrolase; Escherichia coli K-12 ortholog: b3091; Escherichia coli O157:H7 ortholog: z4444.
 
  
 0.990
uidA
Beta-glucuronidase; Escherichia coli K-12 ortholog: b1617; Escherichia coli O157:H7 ortholog: z2621; Belongs to the glycosyl hydrolase 2 family.
 
 
 0.956
exuT
Hexuronate transporter; Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446.
 
   
 0.915
rspB
Starvation sensing protein rspB; Escherichia coli K-12 ortholog: b1580.
     
 0.903
c4828
Putative dehydrogenase; Zinc binding; Residues 29 to 330 of 336 are 33.64 pct identical to residues 45 to 365 of 368 from GenPept.129 : >gb|AAK71492.1| (AY037946) sorbitol dehydrogenase [Prunus cerasus].
     
 0.903
kdgK
2-dehydro-3-deoxygluconokinase; Escherichia coli K-12 ortholog: b3526; Escherichia coli O157:H7 ortholog: z4940.
 
   
 0.877
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
 
  
 0.829
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
     
 0.813
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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