STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sohAHtrA suppressor protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to the YhaV toxin and neutralizes its ribonuclease activity. Also acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression (By similarity). (111 aa)    
Predicted Functional Partners:
yhaV
Hypothetical protein yhaV; Toxic component of a type II toxin-antitoxin (TA) system. Has RNase activity in vitro. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression (By similarity).
 
  
 0.999
yefM
Hypothetical protein yefM; Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of the YoeB mRNA interferase. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor (By similarity).
 
   
 0.740
yoeB
Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor (By similarity).
      
 0.708
yjiK
Hypothetical protein yjiK; Escherichia coli K-12 ortholog: b4333; Escherichia coli O157:H7 ortholog: z5934; Belongs to the YjiK family.
  
     0.697
yhhZ
Hypothetical protein yhhZ; Escherichia coli K-12 ortholog: b3442.
  
     0.677
c3664
Hypothetical protein yeeR; Escherichia coli K-12 ortholog: b2001.
  
     0.663
c2439
Hypothetical protein; Residues 35 to 487 of 489 are 26.20 pct identical to residues 531 to 997 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) putative factor [Escherichia coli K12].
  
   
 0.662
c1274
Hypothetical protein yeeR; Escherichia coli K-12 ortholog: b2001.
  
     0.660
yheB
Probable bifunctional chitinase/lysozyme precursor; Escherichia coli K-12 ortholog: b3338bifunctional; Chitinase; Lysozyme.
  
     0.659
yheK
Probable general secretion pathway protein L; Escherichia coli K-12 ortholog: b3333; Escherichia coli O157:H7 ortholog: z2633.
  
     0.652
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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