STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kefBGlutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)    
Predicted Functional Partners:
yheR
Putative NAD(P)H oxidoreductase yheR; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
 
 
 0.995
yabF
Putative NAD(P)H oxidoreductase yabF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
 
 
 0.957
yheV
Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z4708.
       0.818
mdaB
Modulator of drug activity B; NADPH-specific quinone reductase.
 
 
 0.789
yheT
Hypothetical protein yheT; Escherichia coli K-12 ortholog: b3353; Escherichia coli O157:H7 ortholog: z4714.
 
     0.669
slyD
FKBP-type peptidyl-prolyl cis-trans isomerase slyD; Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in Tat-d [...]
 
     0.641
yheU
Hypothetical protein yheU; Escherichia coli K-12 ortholog: b3354; Escherichia coli O157:H7 ortholog: z4715; Belongs to the UPF0270 family.
       0.627
ybaL
Hypothetical protein ybaL; Escherichia coli K-12 ortholog: b0478; Escherichia coli O157:H7 ortholog: z0597; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
0.610
flgG
Flagellar basal-body rod protein flgG; Distal rod protein; Escherichia coli K-12 ortholog: b1078; Escherichia coli O157:H7 ortholog: z1716; Belongs to the flagella basal body rod proteins family.
    
   0.610
yheS
Hypothetical ABC transporter ATP-binding protein yheS; Genetic data indicate it may be involved in ribosome assembly or function (Probable). Ectopic expression exacerbates the cold- sensitive growth phenotype of a bipA deletion. Belongs to the ABC transporter superfamily. ABCF family. YheS subfamily.
     
 0.589
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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