STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malTMalT Regulatory protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (901 aa)    
Predicted Functional Partners:
ygeX
Putative diaminopropionate ammonia-lyase; Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate (DAP) to form pyruvate and ammonia. The D-isomer of serine is degraded to pyruvate, though very poorly; other amino acids (L-serine, D- and L-threonine, D- and L-beta-Cl-alanine) are not substrates.
      
 0.764
ibpB
16 kDa heat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
    
 
 0.753
malM
Maltose operon periplasmic protein precursor; Escherichia coli K-12 ortholog: b4037; Escherichia coli O157:H7 ortholog: z5635.
 
     0.748
malE
Maltose-binding periplasmic protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.
 
     0.702
lamB
Maltoporin precursor; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.
 
   
 0.700
yhgA
Hypothetical protein yhgA; Escherichia coli K-12 ortholog: b3411; Escherichia coli O157:H7 ortholog: z4766.
      
 0.682
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
      
 0.681
malF
Maltose transport system permease protein malF; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
  
    0.607
flhE
Flagellar protein flhE precursor; Escherichia coli K-12 ortholog: b1878; Escherichia coli O157:H7 ortholog: z2931.
  
     0.596
malS
Alpha-amylase precursor; Escherichia coli K-12 ortholog: b3571; Escherichia coli O157:H7 ortholog: z4996.
 
     0.550
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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