STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
c4284Putative aldolase; Escherichia coli O157:H7 ortholog: z4881. (283 aa)    
Predicted Functional Partners:
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
 
 0.934
agaZ
Putative tagatose 6-phosphate kinase agaZ; Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity.
  
 
 0.924
gatZ
Putative tagatose 6-phosphate kinase gatZ; Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.
  
 
 0.916
gatY
Tagatose-bisphosphate aldolase gatY; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol.
  
  
 
0.916
c4018
Tagatose-bisphosphate aldolase gatY; Escherichia coli K-12 ortholog: b2096; Escherichia coli O157:H7 ortholog: z3259.
  
  
 
0.916
pfkB
6-phosphofructokinase isozyme 2; Escherichia coli K-12 ortholog: b1723; Escherichia coli O157:H7 ortholog: z2752; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.915
agaY
Tagatose-bisphosphate aldolase agaY; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability.
  
  
 
0.915
c4777
Putative conserved protein; Residues 9 to 203 of 209 are 41.08 pct identical to residues 6 to 200 of 587 from MG1655 : b3692.
    
 0.904
eda
KHG/KDPG aldolase; Escherichia coli K-12 ortholog: b1850; Escherichia coli O157:H7 ortholog: z2902; bifunctional; 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase.
    
 0.812
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.748
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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