STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chuWPutative oxygen independent coproporphyrinogen III oxidase; Escherichia coli O157:H7 ortholog: z4914. (445 aa)    
Predicted Functional Partners:
chuX
Hypothetical protein; Escherichia coli O157:H7 ortholog: z4915.
  
 0.992
chuY
Hypothetical protein; Escherichia coli O157:H7 ortholog: z4917.
 
  
 0.960
chuT
Putative Periplasmic binding protein; Escherichia coli O157:H7 ortholog: z4913.
     
 0.857
chuU
Putative permease of iron compound ABC transport system; Escherichia coli O157:H7 ortholog: z4918; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.799
ydbK
Probable pyruvate-flavodoxin oxidoreductase; Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332.
 
  
 0.789
hmuV
Putative ATP-binding protein of ABC transport system; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
     
 0.749
ompW
Outer membrane protein W precursor; Escherichia coli K-12 ortholog: b1256; Escherichia coli O157:H7 ortholog: z2034.
  
  
 0.708
thiC
Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
      
 0.701
hemG
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor.
 
 
 0.622
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.612
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.