STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
c4485Putative PTS enzyme-ii fructose; Residues 11 to 358 of 363 are 53.10 pct identical to residues 5 to 355 of 363 from GenPept.129 : >emb|CAC97469.1| (AL596171) similar to PTS system, fructose-specific enzyme IIC component [Listeria innocua]. (363 aa)    
Predicted Functional Partners:
c4487
Putative phosphotransferase system (PTS), fructose-specific; Residues 1 to 149 of 156 are 48.32 pct identical to residues 6 to 154 of 157 from GenPept.129 : >emb|CAC97471.1| (AL596171) similar to PTS system, fructose-specific enzyme IIA component [Listeria innocua].
 
 0.997
c4486
PTS system, fructose-like-2 IIB component 1; Phosphotransferase enzyme II, B component; Escherichia coli K-12 ortholog: b3950; Escherichia coli O157:H7 ortholog: z5506.
 
 
 0.993
fruK
1-phosphofructokinase; Escherichia coli K-12 ortholog: b2168; Escherichia coli O157:H7 ortholog: z3426; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.987
fruB
PTS system, fructose-specific IIA/FPr component; EIIA-Fru; Escherichia coli K-12 ortholog: b2169; Escherichia coli O157:H7 ortholog: z3427.
 
 0.984
frwB
PTS system, fructose-like-2 IIB component 1; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrwABC PTS system is involved in fructose transport.
  
 0.977
c4484
Putative aldolase; Residues 1 to 283 of 283 are 39.78 pct identical to residues 1 to 283 of 284 from GenPept.129 : >emb|CAD00212.1| (AL591982) similar to fructose-1,6-biphosphate aldolase type II [Listeria monocytogenes].
  
 
 0.976
c4483
Putative aldolase; Escherichia coli O157:H7 ortholog: z5687.
  
 
 0.954
c4482
Hypothetical protein yajF; Escherichia coli K-12 ortholog: b0394; Escherichia coli O157:H7 ortholog: z0493.
    
 0.951
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.922
c4283
Putative phosphocarrier protein; Escherichia coli O157:H7 ortholog: z4879.
  
 
 0.920
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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