STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiEUbiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)    
Predicted Functional Partners:
yleB
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Escherichia coli K-12 ortholog: b0662; Escherichia coli O157:H7 ortholog: z0811.
  
 
 0.988
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase; Escherichia coli K-12 ortholog: b2907; Escherichia coli O157:H7 ortholog: z4244.
  
 
 0.984
yigP
Hypothetical protein yigP; Escherichia coli K-12 ortholog: b3834; Escherichia coli O157:H7 ortholog: z5356.
  
  
 0.965
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.919
yigR
Probable ubiquinone biosynthesis protein ubiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
 
  
 0.917
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.913
wrbA
Flavoprotein wrbA; Trp repressor binding protein; Escherichia coli K-12 ortholog: b1004; Escherichia coli O157:H7 ortholog: z1423.
     
  0.900
c3304
Hypothetical protein; Residues 1 to 183 of 183 are 100.00 pct identical to residues 1 to 183 of 183 from GenPept.129 : >gb|AAG27178.1|AF270497_3 (AF270497) unknown [Escherichia coli].
     
  0.900
ytfG
Hypothetical protein ytfG; Escherichia coli K-12 ortholog: b4211; Escherichia coli O157:H7 ortholog: z5822.
     
  0.900
yigC
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
 
  
 0.863
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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