STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdhCDP-diacylglycerol pyrophosphatase; Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463. (315 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; Escherichia coli K-12 ortholog: b0175; Escherichia coli O157:H7 ortholog: z0186; Belongs to the CDS family.
  
  
 0.913
ynbB
Hypothetical protein ynbB; Escherichia coli K-12 ortholog: b1409; Escherichia coli O157:H7 ortholog: z2318.
     
  0.900
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Escherichia coli K-12 ortholog: b2585; Escherichia coli O157:H7 ortholog: z3870.
     
  0.900
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b3018; Escherichia coli O157:H7 ortholog: z4372; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
     
  0.900
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
     
  0.900
sbp
Sulfate-binding protein precursor; Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462.
  
    0.815
c4868
Hypothetical protein.
       0.773
sulA
Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.681
ypfN
Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z3731.
  
     0.660
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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