STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgaEProbable sugar isomerase sgaE; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization. (244 aa)    
Predicted Functional Partners:
sgaU
Putative hexulose-6-phosphate isomerase; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family.
  
 0.998
araB
L-ribulokinase; Escherichia coli K-12 ortholog: b0063; Escherichia coli O157:H7 ortholog: z0072.
 
 
 0.990
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
 
 
 0.988
sgbU
Putative hexulose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b3582; Escherichia coli O157:H7 ortholog: z5806.
  
 0.988
xylB
Xylulose kinase; Escherichia coli K-12 ortholog: b3564; Escherichia coli O157:H7 ortholog: z4989.
  
 
 0.919
sgbE
Probable sugar isomerase sgbE; Escherichia coli K-12 ortholog: b3583; Escherichia coli O157:H7 ortholog: z0069.
  
 
 
0.909
rpe
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.904
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
  
  
 
0.902
sgaH
Probable hexulose-6-phosphate synthase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily.
 
  
 0.891
yjfR
Hypothetical protein yjfR; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family.
 
   
 0.889
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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