STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yggJHypothetical protein yggJ; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity); Belongs to the RNA methyltransferase RsmE family. (252 aa)    
Predicted Functional Partners:
yebU
Hypothetical protein yebU; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
  
  
 0.810
gshB
Glutathione synthetase; Escherichia coli K-12 ortholog: b2947; Escherichia coli O157:H7 ortholog: z4292.
  
  
 0.806
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
 
  
 0.794
yqgF
Hypothetical protein yqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
 
   
 0.764
yqgE
Protein yqgE; Escherichia coli K-12 ortholog: b2948; Escherichia coli O157:H7 ortholog: z4293; Belongs to the UPF0301 (AlgH) family.
     
 0.699
ybeA
Hypothetical protein ybeA; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
  
   
 0.685
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.683
endA
Endonuclease I precursor; Escherichia coli K-12 ortholog: b2945; Escherichia coli O157:H7 ortholog: z4290.
       0.658
sun
SUN protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.594
gidB
Methyltransferase gidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
  
 0.589
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.