STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182PPS91-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1263 aa)    
Predicted Functional Partners:
A0A182PLD1
Uncharacterized protein.
    
 0.958
A0A182P4I0
Uncharacterized protein.
   
  0.940
A0A182P7J7
IPPc domain-containing protein.
   
 
 0.906
A0A182PNT9
CaMKII_AD domain-containing protein.
   
 
 0.903
A0A182NZM7
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 
0.902
A0A182P4H3
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.901
A0A182PB09
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.901
A0A182PGY2
WD_REPEATS_REGION domain-containing protein.
     
 0.900
A0A182PGC8
SAC domain-containing protein.
   
 
 0.897
A0A182PDI3
Inositol-1-monophosphatase.
     
 0.896
Your Current Organism:
Anopheles epiroticus
NCBI taxonomy Id: 199890
Other names: A. epiroticus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.