node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG17232.1 | SDG30986.1 | SAMN05216553_1068 | SAMN05216553_10747 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit alpha. | 0.992 |
SDG17232.1 | SDH11273.1 | SAMN05216553_1068 | SAMN05216553_11642 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit epsilon. | 0.956 |
SDG17232.1 | SDH23191.1 | SAMN05216553_1068 | SAMN05216553_11847 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit delta'. | 0.998 |
SDG17232.1 | SDH24143.1 | SAMN05216553_1068 | SAMN05216553_11899 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit beta. | 0.994 |
SDG17232.1 | SDH56467.1 | SAMN05216553_1068 | SAMN05216553_1292 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.995 |
SDG17232.1 | dnaE2 | SAMN05216553_1068 | SAMN05216553_102655 | DNA polymerase III, delta subunit. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.982 |
SDG17232.1 | dnaX | SAMN05216553_1068 | SAMN05216553_118152 | DNA polymerase III, delta subunit. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.998 |
SDG17232.1 | polA | SAMN05216553_1068 | SAMN05216553_113122 | DNA polymerase III, delta subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.672 |
SDG17232.1 | topA | SAMN05216553_1068 | SAMN05216553_11850 | DNA polymerase III, delta subunit. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.604 |
SDG30986.1 | SDG17232.1 | SAMN05216553_10747 | SAMN05216553_1068 | DNA polymerase-3 subunit alpha. | DNA polymerase III, delta subunit. | 0.992 |
SDG30986.1 | SDH11273.1 | SAMN05216553_10747 | SAMN05216553_11642 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit epsilon. | 0.949 |
SDG30986.1 | SDH23191.1 | SAMN05216553_10747 | SAMN05216553_11847 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit delta'. | 0.992 |
SDG30986.1 | SDH24143.1 | SAMN05216553_10747 | SAMN05216553_11899 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit beta. | 0.986 |
SDG30986.1 | SDH56467.1 | SAMN05216553_10747 | SAMN05216553_1292 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.991 |
SDG30986.1 | dnaE2 | SAMN05216553_10747 | SAMN05216553_102655 | DNA polymerase-3 subunit alpha. | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.807 |
SDG30986.1 | dnaX | SAMN05216553_10747 | SAMN05216553_118152 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.994 |
SDG30986.1 | polA | SAMN05216553_10747 | SAMN05216553_113122 | DNA polymerase-3 subunit alpha. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.727 |
SDG30986.1 | topA | SAMN05216553_10747 | SAMN05216553_11850 | DNA polymerase-3 subunit alpha. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.598 |
SDH11273.1 | SDG17232.1 | SAMN05216553_11642 | SAMN05216553_1068 | DNA polymerase-3 subunit epsilon. | DNA polymerase III, delta subunit. | 0.956 |
SDH11273.1 | SDG30986.1 | SAMN05216553_11642 | SAMN05216553_10747 | DNA polymerase-3 subunit epsilon. | DNA polymerase-3 subunit alpha. | 0.949 |