STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfAUnannotated protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (356 aa)    
Predicted Functional Partners:
prmC
Unannotated protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
 0.998
rplM
Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.974
rplT
Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.967
rpsI
Unannotated protein; Belongs to the universal ribosomal protein uS9 family.
 
 
 0.961
rplQ
Unannotated protein.
 
 
 0.954
rpmA
Unannotated protein; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.952
rplC
Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 
 0.951
rpsG
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.950
rplO
Unannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 
 
 0.948
rplD
Unannotated protein; Forms part of the polypeptide exit tunnel.
 
 
 0.941
Your Current Organism:
Paraliobacillus ryukyuensis
NCBI taxonomy Id: 200904
Other names: DSM 15140, IAM 15001, JCM 21472, NBRC 100001, NRIC 0520, P. ryukyuensis, Paraliobacillus ryukyuensis Ishikawa et al. 2003, strain O15-7
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