| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DMN91_001124 | DMN91_006055 | A0A026WV52 | A0A026WPW1 | C-1-tetrahydrofolate synthase, cytoplasmic. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.944 |
| DMN91_001124 | DMN91_008833 | A0A026WV52 | A0A026WIX7 | C-1-tetrahydrofolate synthase, cytoplasmic. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.996 |
| DMN91_001124 | X777_00336 | A0A026WV52 | A0A026WU32 | C-1-tetrahydrofolate synthase, cytoplasmic. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.966 |
| DMN91_001124 | X777_04722 | A0A026WV52 | A0A026X1M0 | C-1-tetrahydrofolate synthase, cytoplasmic. | Methionyl-tRNA formyltransferase, mitochondrial. | 0.985 |
| DMN91_001124 | X777_05986 | A0A026WV52 | A0A026WER7 | C-1-tetrahydrofolate synthase, cytoplasmic. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.982 |
| DMN91_001124 | X777_07887 | A0A026WV52 | A0A026X2D7 | C-1-tetrahydrofolate synthase, cytoplasmic. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| DMN91_001124 | X777_09469 | A0A026WV52 | A0A026W6V9 | C-1-tetrahydrofolate synthase, cytoplasmic. | Thymidylate synthase. | 0.976 |
| DMN91_001124 | X777_12985 | A0A026WV52 | A0A026VYF2 | C-1-tetrahydrofolate synthase, cytoplasmic. | Bifunctional purine biosynthesis protein PURH. | 0.997 |
| DMN91_001124 | X777_16171 | A0A026WV52 | A0A026WVF9 | C-1-tetrahydrofolate synthase, cytoplasmic. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.966 |
| DMN91_006055 | DMN91_001124 | A0A026WPW1 | A0A026WV52 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | C-1-tetrahydrofolate synthase, cytoplasmic. | 0.944 |
| DMN91_006055 | DMN91_008833 | A0A026WPW1 | A0A026WIX7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.943 |
| DMN91_006055 | X777_04722 | A0A026WPW1 | A0A026X1M0 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Methionyl-tRNA formyltransferase, mitochondrial. | 0.716 |
| DMN91_006055 | X777_04836 | A0A026WPW1 | A0A026WGU0 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydropteridine reductase. | 0.439 |
| DMN91_006055 | X777_05986 | A0A026WPW1 | A0A026WER7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.992 |
| DMN91_006055 | X777_07887 | A0A026WPW1 | A0A026X2D7 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.747 |
| DMN91_006055 | X777_09469 | A0A026WPW1 | A0A026W6V9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase. | 0.985 |
| DMN91_006055 | X777_12985 | A0A026WPW1 | A0A026VYF2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Bifunctional purine biosynthesis protein PURH. | 0.732 |
| DMN91_006055 | X777_16171 | A0A026WPW1 | A0A026WVF9 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.534 |
| DMN91_008833 | DMN91_001124 | A0A026WIX7 | A0A026WV52 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | C-1-tetrahydrofolate synthase, cytoplasmic. | 0.996 |
| DMN91_008833 | DMN91_006055 | A0A026WIX7 | A0A026WPW1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.943 |