SHE98816.1 protein (Streptoalloteichus hindustanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SHE98816.1

Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase. (146 aa)

Predicted Functional Partners:

SHF82862.1

0.813

SHF60905.1

0.796

SHG36711.1

0.796

SHG36773.1

0.796

SHH10169.1

0.796

SHF31476.1

0.784

SHF36332.1

0.744

SHE45964.1

0.727

SHE47044.1

0.712

SHF85181.1

0.712

Your Current Organism:

Streptoalloteichus hindustanus

NCBI taxonomy Id: 2017
Other names: ATCC 31217, DSM 44523, IFO 15115, JCM 3268, NBRC 15115, NRRL B-11280, S. hindustanus, Streptalloteichus hindustanensis, Streptalloteichus hindustanus, Streptoalloteichus hindustanensis, VKM Ac-683, strain C677-91

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHE45964.1	SHE47044.1	SAMN05444320_101147	SAMN05444320_101175	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	0.550
SHE45964.1	SHE98816.1	SAMN05444320_101147	SAMN05444320_102178	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	0.727
SHE45964.1	SHF31476.1	SAMN05444320_101147	SAMN05444320_103189	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Glutamate synthase (NADPH/NADH) large chain.	0.979
SHE45964.1	SHF85181.1	SAMN05444320_101147	SAMN05444320_105228	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Ferredoxin-NADP reductase.	0.550
SHE47044.1	SHE45964.1	SAMN05444320_101175	SAMN05444320_101147	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.550
SHE47044.1	SHE98816.1	SAMN05444320_101175	SAMN05444320_102178	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	0.712
SHE47044.1	SHF31476.1	SAMN05444320_101175	SAMN05444320_103189	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Glutamate synthase (NADPH/NADH) large chain.	0.534
SHE47044.1	SHF60905.1	SAMN05444320_101175	SAMN05444320_104262	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Reductase C-terminal.	0.716
SHE47044.1	SHF82862.1	SAMN05444320_101175	SAMN05444320_105142	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Reductase C-terminal.	0.907
SHE47044.1	SHF85181.1	SAMN05444320_101175	SAMN05444320_105228	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Ferredoxin-NADP reductase.	0.780
SHE47044.1	SHG36711.1	SAMN05444320_101175	SAMN05444320_108173	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Assimilatory nitrate reductase electron transfer subunit.	0.716
SHE47044.1	SHG36773.1	SAMN05444320_101175	SAMN05444320_108175	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Nitrite reductase (NADH) large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.716
SHE47044.1	SHH10169.1	SAMN05444320_101175	SAMN05444320_12230	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	Reductase C-terminal.	0.716
SHE98816.1	SHE45964.1	SAMN05444320_102178	SAMN05444320_101147	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.727
SHE98816.1	SHE47044.1	SAMN05444320_102178	SAMN05444320_101175	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.	0.712
SHE98816.1	SHF31476.1	SAMN05444320_102178	SAMN05444320_103189	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	Glutamate synthase (NADPH/NADH) large chain.	0.784
SHE98816.1	SHF36332.1	SAMN05444320_102178	SAMN05444320_103354	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.	0.744
SHE98816.1	SHF60905.1	SAMN05444320_102178	SAMN05444320_104262	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	Reductase C-terminal.	0.796
SHE98816.1	SHF82862.1	SAMN05444320_102178	SAMN05444320_105142	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	Reductase C-terminal.	0.813
SHE98816.1	SHF85181.1	SAMN05444320_102178	SAMN05444320_105228	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase.	Ferredoxin-NADP reductase.	0.712

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.859

expected number of edges:

10

PPI enrichment p-value:

0.105

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032957

Inositol trisphosphate metabolic process

4 of 5

3.24

4.19

2.40e-08

GO:0070266

Necroptotic process

4 of 13

2.83

3.59

2.27e-07

GO:0006066

Alcohol metabolic process

5 of 291

1.58

1.61

0.00014

GO:0052746

Inositol phosphorylation

2 of 3

3.16

1.54

0.0017

GO:0032958

Inositol phosphate biosynthetic process

2 of 14

2.5

0.97

0.0167

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000825

Inositol tetrakisphosphate 6-kinase activity

4 of 4

3.34

4.61

4.39e-09

GO:0051766

Inositol trisphosphate kinase activity

4 of 9

2.99

4.26

1.49e-08

GO:0003993

Acid phosphatase activity

3 of 7

2.97

2.88

5.66e-06

GO:0102732

myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

GO:0052726

inositol-1,3,4-trisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:30075

Acid phosphatase activity, and Alkaline phosphatase activity

6 of 14

2.97

6.68

3.23e-13

CL:30076

Acid phosphatase activity, and Phosphodiesterase I activity

4 of 7

3.1

4.32

1.27e-08

CL:38050

Inositol trisphosphate kinase activity, and Inositol tetrakisphosphate phosphatase activity

4 of 17

2.71

3.62

1.72e-07

CL:38074

Inositol phosphorylation, and Inositol tetrakisphosphate 5-kinase activity

3 of 5

3.12

2.98

3.89e-06

CL:30089

Alkaline phosphatase activity, and Acid phosphatase activity

2 of 7

2.8

1.41

0.0028

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00730

Thiamine metabolism

4 of 21

2.62

3.84

5.24e-08

map00740

Riboflavin metabolism

3 of 19

2.54

2.8

5.30e-06

map00562

Inositol phosphate metabolism

5 of 169

1.81

2.66

5.39e-07

map04070

Phosphatidylinositol signaling system

4 of 181

1.68

1.89

4.16e-05

map01100

Metabolic pathways

11 of 3242

0.87

0.96

5.24e-08

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1483249

Inositol phosphate metabolism

5 of 70

2.19

3.28

1.94e-07

MAP-196819

Vitamin B1 (thiamin) metabolism

2 of 5

2.94

1.47

0.0022

MAP-1855191

Synthesis of IPs in the nucleus

2 of 7

2.8

1.41

0.0028

MAP-1855167

Synthesis of pyrophosphates in the cytosol

2 of 10

2.64

1.3

0.0042

MAP-196849

Metabolism of water-soluble vitamins and cofactors

3 of 192

1.53

0.79

0.0228

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00149

Calcineurin-like phosphoesterase

3 of 14

2.67

2.15

0.00011

PF05770

Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain

2 of 2

3.34

1.6

0.0013

PF03770

Inositol polyphosphate kinase

2 of 9

2.69

1.15

0.0081

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About