STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF13494.1Tartronate-semialdehyde synthase; Belongs to the TPP enzyme family. (572 aa)    
Predicted Functional Partners:
SHF13427.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.980
SHF13461.1
2-hydroxy-3-oxopropionate reductase.
 
 
 0.968
SHF06027.1
Malate synthase; Belongs to the malate synthase family.
    
 0.875
SHE73771.1
Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.843
SHF13526.1
Glycerate kinase; Belongs to the glycerate kinase type-1 family.
  
  
 0.809
SHG05866.1
Acetolactate synthase, small subunit.
 
     0.780
SHF46474.1
3-hydroxyisobutyrate dehydrogenase.
  
 
 0.771
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
     0.740
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
     0.729
SHF89196.1
3-hydroxyisobutyrate dehydrogenase.
 
 
 0.539
Your Current Organism:
Streptoalloteichus hindustanus
NCBI taxonomy Id: 2017
Other names: ATCC 31217, DSM 44523, IFO 15115, JCM 3268, NBRC 15115, NRRL B-11280, S. hindustanus, Streptalloteichus hindustanensis, Streptalloteichus hindustanus, Streptoalloteichus hindustanensis, VKM Ac-683, strain C677-91
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